Dr. 乔西LoRicco
research scientist - sponsored research
地址:
Center for Integrated Sciences (CIS), Room 143
Department of 医学杂志ogy
Skidmore Microscopy Imaging Center (SMIC)
Department of 医学杂志ogy
Skidmore College
Saratoga Springs, NY 12866
电话: 518 - 580 - tbd
电子邮件: jloricco@kadinuobeier.com
教育:
- B.S. 生物化学 & Biophysics (2014) Rensselaer Polytechnic Institute (Troy, NY)
- Ph.D. 生物化学 & Biophysics (2019) Rensselaer Polytechnic Institute (Troy, NY)
- Postdoctoral Research (2019-2021) INSA de Lyon (France)
Research Interests:
Past Research Interests: My PhD research focused on understanding the aggregation of protein into amyloid fibrils which are associated with many neurodegenerative diseases such as Alzheimer’s. My previous postdoctoral studies looked at the structure of archaeal membranes and looked for possible adaptation mechanisms of these membranes to high pressure and temperature conditions.
Current Research Interests: My current research takes place in the lab of Dr. Domozych studying the evolution of the cell wall in plants using the Zygnematophyte green algae, Penium margaritaceum, as a model organism. Penium displays many similarities to land plants, including the production of many cell wall components and belongs to the group of algae most closely related to land plants. Understanding the membrane trafficking network and secretion of cell wall materials in Penium may provide insights into how ancestors of these organisms were able to colonize land, and give rise to land plants. My research probes the secretory network of Penium using both cell biology, and chemical biology approaches. Research techniques include: light microscopy, confocal laser scanning microscopy, transmission election microscopy (TEM), scanning electron microscopy (SEM) and immunocytochemistry, as well as other biochemical methodologies.
Selected Publications:
- LoRicco J.G., Salvador-Castell, M.B.彼得斯，J.P.M. (2020) Frontiers in 化学istry 8, 594039, doi: 10.3389 / fchem.2020.594039
- 徐,年代., LoRicco J.G.主教，A.C.詹姆斯·N.A.黄，W.H.麦卡勒姆，S.A.罗安，n.n.R.Makhatadze, G.I. (2020) Sequence-independent recognition of the amyloid structural motif by GFP 蛋白家族. P.N.A.S 117, 22122–27, doi: 10.1073 / pnas.2001457117
- LoRicco J.G.，徐，C. S.尼德曼，J.Bergkvist, M.格林，W。. C.罗安，n.n. R., and Makhatadze, G. I. (2016) Gallic Acid Is an Antagonist of Semen Amyloid Fibrils That Enhance HIV-1 Infection., J. 医学杂志. 化学. 291, 14045–55, doi: 10.1074 / jbc.M116.718684
Selected Awards:
- NIH/NIGMS Pre-doctoral fellowship in Biomolecular Sciences (2015-2017)